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Protein-Precursor tRNA Contact Leads to Sequence-Specific Recognition of 5’ Leaders by Bacterial Ribonuclease P
Bacterial ribonuclease P (RNase P) catalyzes cleavage of 5’ leader sequences from precursor tRNAs (pre-tRNAs). Previously, all known substrate nucleotide specificity in this system derived from RNA-RNA interactions with the RNase P RNA subunit (PRNA). Here, we demonstrate that pre-tRNA binding affin...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2829246/ https://ncbi.nlm.nih.gov/pubmed/19932118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.11.039 |
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