Protein component of the ribozyme ribonuclease P alters substrate recognition by directly contacting precursor tRNA

The protein component of ribonuclease P (RNase P) binds to the RNA subunit, forming a functional ribonucleoprotein complex in vivo and enhancing the affinity of the precursor tRNA (pre-tRNA) substrate. Photocrosslinking experiments with pre-tRNA bound to RNase P reconstituted with the protein compon...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Niranjanakumari, S., Stams, Travis, Crary, Sharon M., Christianson, David W., Fierke, Carol A.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1998
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC28022/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9860948/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.26.15212
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