Protein component of the ribozyme ribonuclease P alters substrate recognition by directly contacting precursor tRNA
The protein component of ribonuclease P (RNase P) binds to the RNA subunit, forming a functional ribonucleoprotein complex in vivo and enhancing the affinity of the precursor tRNA (pre-tRNA) substrate. Photocrosslinking experiments with pre-tRNA bound to RNase P reconstituted with the protein compon...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
1998
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC28022/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9860948/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.26.15212 |
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