Differential transport of platinum compounds by the human organic cation transporter hOCT2 (hSLC22A2)

BACKGROUND: Solute carriers (SLCs), in particular organic cation transporters (OCTs), have been implicated in the cellular uptake of platinum-containing anticancer compounds. The activity of these carriers may determine the pharmacokinetics and the severity of side effects, including neuro- and neph...

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Main Authors: Burger, H, Zoumaro-Djayoon, A, Boersma, AWM, Helleman, J, Berns, EMJJ, Mathijssen, RHJ, Loos, WJ, Wiemer, EAC
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2010
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Research Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829215/
https://ncbi.nlm.nih.gov/pubmed/20067471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00569.x
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