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Pharmacophore modelling of stereoselective binding to the human organic cation transporter (hOCT1)
BACKGROUND AND PURPOSE: The human organic cation transporter-1 (hOCT1) is a polyspecific transporter that plays a role in drug distribution, metabolism and excretion. Previous studies have demonstrated that hOCT1 binding can be stereoselective, but the mechanism for stereochemical recognition has no...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2189821/ https://ncbi.nlm.nih.gov/pubmed/17592512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707341 |
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