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Potent inhibition of human organic cation transporter 2 (hOCT2) by β-carboline alkaloids

1. Beta-carbolines are indole alkaloids with a wide range of pharmacological and toxicological activities. Beta-carbolines are structurally related to the neurotoxin 1-methyl-4-phenylpyridinium (MPP+), a known substrate of organic cation transporters (OCTs). The goal of this study is to determine th...

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Detalhes bibliográficos
Publicado no:Xenobiotica
Main Authors: Wagner, David J., Duan, Haichuan, Chapron, Alenka, Lee, Richard W., Wang, Joanne
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5648609/
https://ncbi.nlm.nih.gov/pubmed/27977936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/00498254.2016.1271160
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