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Direct conversion of fibroblasts to functional neurons by defined factors

Cellular differentiation and lineage commitment are considered robust and irreversible processes during development. Recent work has shown that mouse and human fibroblasts can be reprogrammed to a pluripotent state with a combination of four transcription factors. This raised the question of whether...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Vierbuchen, Thomas, Ostermeier, Austin, Pang, Zhiping P., Kokubu, Yuko, Südhof, Thomas C., Wernig, Marius
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829121/
https://ncbi.nlm.nih.gov/pubmed/20107439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08797
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