Llwytho...

Direct conversion of fibroblasts to functional neurons by defined factors

Cellular differentiation and lineage commitment are considered robust and irreversible processes during development. Recent work has shown that mouse and human fibroblasts can be reprogrammed to a pluripotent state with a combination of four transcription factors. This raised the question of whether...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Vierbuchen, Thomas, Ostermeier, Austin, Pang, Zhiping P., Kokubu, Yuko, Südhof, Thomas C., Wernig, Marius
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829121/
https://ncbi.nlm.nih.gov/pubmed/20107439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08797
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