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Preservation of cortical sortilin protein levels in MCI and Alzheimer’s disease
The nerve growth factor (NGF) precursor protein proNGF is the predominant NGF moiety found in the human neocortex and exhibits pro-apoptotic properties when bound to the p75(NTR) neurotrophin receptor in the presence of sortilin, a Vps10p domain trafficking protein. Recently studies have shown that...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2829104/ https://ncbi.nlm.nih.gov/pubmed/20085800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2010.01.023 |
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