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Preservation of cortical sortilin protein levels in MCI and Alzheimer’s disease

The nerve growth factor (NGF) precursor protein proNGF is the predominant NGF moiety found in the human neocortex and exhibits pro-apoptotic properties when bound to the p75(NTR) neurotrophin receptor in the presence of sortilin, a Vps10p domain trafficking protein. Recently studies have shown that...

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Bibliografske podrobnosti
Main Authors: Mufson, Elliott J., Wuu, Joanne, Counts, Scott E., Nykjaer, Anders
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829104/
https://ncbi.nlm.nih.gov/pubmed/20085800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2010.01.023
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