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Cdk2 Is Required for p53-Independent G(2)/M Checkpoint Control
The activation of phase-specific cyclin-dependent kinases (Cdks) is associated with ordered cell cycle transitions. Among the mammalian Cdks, only Cdk1 is essential for somatic cell proliferation. Cdk1 can apparently substitute for Cdk2, Cdk4, and Cdk6, which are individually dispensable in mice. It...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2829054/ https://ncbi.nlm.nih.gov/pubmed/20195506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000863 |
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