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Cdk2 Is Required for p53-Independent G(2)/M Checkpoint Control
The activation of phase-specific cyclin-dependent kinases (Cdks) is associated with ordered cell cycle transitions. Among the mammalian Cdks, only Cdk1 is essential for somatic cell proliferation. Cdk1 can apparently substitute for Cdk2, Cdk4, and Cdk6, which are individually dispensable in mice. It...
שמור ב:
| Main Authors: | , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Public Library of Science
2010
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2829054/ https://ncbi.nlm.nih.gov/pubmed/20195506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000863 |
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