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Cdk2 Is Required for p53-Independent G(2)/M Checkpoint Control

The activation of phase-specific cyclin-dependent kinases (Cdks) is associated with ordered cell cycle transitions. Among the mammalian Cdks, only Cdk1 is essential for somatic cell proliferation. Cdk1 can apparently substitute for Cdk2, Cdk4, and Cdk6, which are individually dispensable in mice. It...

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Bibliografski detalji
Glavni autori: Chung, Jon H., Bunz, Fred
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829054/
https://ncbi.nlm.nih.gov/pubmed/20195506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000863
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