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Bias correction and Bayesian analysis of aggregate counts in SAGE libraries

BACKGROUND: Tag-based techniques, such as SAGE, are commonly used to sample the mRNA pool of an organism's transcriptome. Incomplete digestion during the tag formation process may allow for multiple tags to be generated from a given mRNA transcript. The probability of forming a tag varies with...

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Autori principali: Zaretzki, Russell L, Gilchrist, Michael A, Briggs, William M, Armagan, Artin
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829012/
https://ncbi.nlm.nih.gov/pubmed/20128916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-72
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