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Bias correction and Bayesian analysis of aggregate counts in SAGE libraries

BACKGROUND: Tag-based techniques, such as SAGE, are commonly used to sample the mRNA pool of an organism's transcriptome. Incomplete digestion during the tag formation process may allow for multiple tags to be generated from a given mRNA transcript. The probability of forming a tag varies with...

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Autors principals: Zaretzki, Russell L, Gilchrist, Michael A, Briggs, William M, Armagan, Artin
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829012/
https://ncbi.nlm.nih.gov/pubmed/20128916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-72
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