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Analysis and correction of compositional bias in sparse sequencing count data

BACKGROUND: Count data derived from high-throughput deoxy-ribonucliec acid (DNA) sequencing is frequently used in quantitative molecular assays. Due to properties inherent to the sequencing process, unnormalized count data is compositional, measuring relative and not absolute abundances of the assay...

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Bibliografski detalji
Izdano u:BMC Genomics
Glavni autori: Kumar, M. Senthil, Slud, Eric V., Okrah, Kwame, Hicks, Stephanie C., Hannenhalli, Sridhar, Corrada Bravo, Héctor
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219007/
https://ncbi.nlm.nih.gov/pubmed/30400812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-5160-5
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