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Analysis and correction of compositional bias in sparse sequencing count data

BACKGROUND: Count data derived from high-throughput deoxy-ribonucliec acid (DNA) sequencing is frequently used in quantitative molecular assays. Due to properties inherent to the sequencing process, unnormalized count data is compositional, measuring relative and not absolute abundances of the assay...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Kumar, M. Senthil, Slud, Eric V., Okrah, Kwame, Hicks, Stephanie C., Hannenhalli, Sridhar, Corrada Bravo, Héctor
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219007/
https://ncbi.nlm.nih.gov/pubmed/30400812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-5160-5
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