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Bias correction and Bayesian analysis of aggregate counts in SAGE libraries

BACKGROUND: Tag-based techniques, such as SAGE, are commonly used to sample the mRNA pool of an organism's transcriptome. Incomplete digestion during the tag formation process may allow for multiple tags to be generated from a given mRNA transcript. The probability of forming a tag varies with...

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Detalhes bibliográficos
Main Authors: Zaretzki, Russell L, Gilchrist, Michael A, Briggs, William M, Armagan, Artin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829012/
https://ncbi.nlm.nih.gov/pubmed/20128916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-72
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