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BAG1 restores formation of functional DJ-1 L166P dimers and DJ-1 chaperone activity
Mutations in the gene coding for DJ-1 protein lead to early-onset recessive forms of Parkinson’s disease. It is believed that loss of DJ-1 function is causative for disease, although the function of DJ-1 still remains a matter of controversy. We show that DJ-1 is localized in the cytosol and is asso...
Tallennettuna:
| Päätekijät: | , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
The Rockefeller University Press
2010
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2828921/ https://ncbi.nlm.nih.gov/pubmed/20156966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200904103 |
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