Interaction of BAG1 and Hsp70 Mediates Neuroprotectivity and Increases Chaperone Activity

It was recently shown that Bcl-2-associated athanogene 1 (BAG1) is a potent neuroprotectant as well as a marker of neuronal differentiation. Since there appears to exist an equilibrium within the cell between BAG1 binding to heat shock protein 70 (Hsp70) and BAG1 binding to Raf-1 kinase, we hypothes...

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Autori principali: Liman, Jan, Ganesan, Sundar, Dohm, Christoph P., Krajewski, Stan, Reed, John C., Bähr, Mathias, Wouters, Fred S., Kermer, Pawel
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2005
Soggetti:
Signal Transduction
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084317/
https://ncbi.nlm.nih.gov/pubmed/15831476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.9.3715-3725.2005
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