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The Folding Pathway of a Single Domain in a Multidomain Protein is not Affected by Its Neighbouring Domain

Domains are the structural, functional, and evolutionary components of proteins. Most folding studies to date have concentrated on the folding of single domains, but more than 70% of human proteins contain more than one domain, and interdomain interactions can affect both the stability and the foldi...

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Библиографические подробности
Главные авторы: Batey, Sarah, Clarke, Jane
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828540/
https://ncbi.nlm.nih.gov/pubmed/18371978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.02.032
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