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Complex Folding Kinetics of a Multidomain Protein

Spectrin domains are three-helix bundles, commonly found in large tandem arrays. Equilibrium studies have shown that spectrin domains are significantly stabilized by their neighbors. In this work we show that domain:domain interactions can also have profound effects on their kinetic behavior. We hav...

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Detalhes bibliográficos
Main Authors: Batey, Sarah, Scott, Kathryn A., Clarke, Jane
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1386790/
https://ncbi.nlm.nih.gov/pubmed/16387757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.072710
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