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Apparent cooperativity in the folding of multidomain proteins depends on the relative rates of folding of the constituent domains

Approximately 75% of eukaryotic proteins contain more than one so-called independently folding domain. However, there have been relatively few systematic studies to investigate the effect of interdomain interactions on protein stability and fewer still on folding kinetics. We present the folding of...

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Bibliographic Details
Main Authors: Batey, Sarah, Clarke, Jane
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636339/
https://ncbi.nlm.nih.gov/pubmed/17108086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604580103
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