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Apparent cooperativity in the folding of multidomain proteins depends on the relative rates of folding of the constituent domains

Approximately 75% of eukaryotic proteins contain more than one so-called independently folding domain. However, there have been relatively few systematic studies to investigate the effect of interdomain interactions on protein stability and fewer still on folding kinetics. We present the folding of...

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Bibliografski detalji
Glavni autori: Batey, Sarah, Clarke, Jane
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636339/
https://ncbi.nlm.nih.gov/pubmed/17108086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604580103
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