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Folding pathway of a multidomain protein depends on its topology of domain connectivity
How do the folding mechanisms of multidomain proteins depend on protein topology? We addressed this question by developing an Ising-like structure-based model and applying it for the analysis of free-energy landscapes and folding kinetics of an example protein, Escherichia coli dihydrofolate reducta...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4234588/ https://ncbi.nlm.nih.gov/pubmed/25267632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1406244111 |
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