Robust atrophy rate measurement in Alzheimer’s disease using multi-site serial MRI: Tissue-specific intensity normalization and parameter selection

We describe an improved method of measuring brain atrophy rates from serial MRI for multi-site imaging studies of Alzheimer’s disease (AD). The method (referred to as KN-BSI) improves an existing brain atrophy measurement technique—the boundary shift integral (classic-BSI), by performing tissue-spec...

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Detaylı Bibliyografya
Asıl Yazarlar: Leung, Kelvin K., Clarkson, Matthew J., Bartlett, Jonathan W., Clegg, Shona, Jack, Clifford R., Weiner, Michael W., Fox, Nick C., Ourselin, Sébastien
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828361/
https://ncbi.nlm.nih.gov/pubmed/20034579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2009.12.059
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