Presymptomatic atrophy in autosomal dominant Alzheimer’s disease: A serial MRI study

INTRODUCTION: Identifying at what point atrophy rates first change in Alzheimer’s disease is important for informing design of presymptomatic trials. METHODS: Serial T1-weighed magnetic resonance imaging scans of 94 participants (28 noncarriers, 66 carriers) from the Dominantly Inherited Alzheimer N...

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Publicado en:Alzheimers Dement
Main Authors: Kinnunen, Kirsi M., Cash, David M., Poole, Teresa, Frost, Chris, Benzinger, Tammie L. S., Ahsan, R. Laila, Leung, Kelvin K., Cardoso, M. Jorge, Modat, Marc, Malone, Ian B., Morris, John C., Bateman, Randall J., Marcus, Daniel S., Goate, Alison, Salloway, Stephen P., Correia, Stephen, Sperling, Reisa A., Chhatwal, Jasmeer P., Mayeux, Richard P., Brickman, Adam M., Martins, Ralph N., Farlow, Martin R., Ghetti, Bernardino, Saykin, Andrew J., Jack, Clifford R., Schofield, Peter R., McDade, Eric, Weiner, Michael W., Ringman, John M., Thompson, Paul M., Masters, Colin L., Rowe, Christopher C., Rossor, Martin N., Ourselin, Sebastien, Fox, Nick C.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5751893/
https://ncbi.nlm.nih.gov/pubmed/28738187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2017.06.2268
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