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Robust atrophy rate measurement in Alzheimer’s disease using multi-site serial MRI: Tissue-specific intensity normalization and parameter selection
We describe an improved method of measuring brain atrophy rates from serial MRI for multi-site imaging studies of Alzheimer’s disease (AD). The method (referred to as KN-BSI) improves an existing brain atrophy measurement technique—the boundary shift integral (classic-BSI), by performing tissue-spec...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2828361/ https://ncbi.nlm.nih.gov/pubmed/20034579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2009.12.059 |
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