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Lysyl Oxidase Enhances Elastin Synthesis and Matrix Formation by Vascular Smooth Muscle Cells
Lysyl oxidase (LOX) is a copper-dependent enzyme which initiates covalent crosslinking of elastin precursors by oxidizing peptidyl lysine to aminoadipic semialdehydes. Previous studies have shown LOX deficiency to affect crosslinking of elastin and collagen in vivo, resulting in disorganized connect...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2828049/ https://ncbi.nlm.nih.gov/pubmed/19813219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/term.214 |
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