Lysyl Oxidase Oxidizes Cell Membrane Proteins and Enhances the Chemotactic Response of Vascular Smooth Muscle Cells

Lysyl oxidase (LOX) is a potent chemokine inducing the migration of varied cell types. Here we demonstrate that inhibition of LOX activity by β-aminopropionitrile (BAPN) in cultured rat aortic smooth muscle cells (SMCs) reduced the chemotactic response and sensitivity of these cells toward LOX and t...

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Main Authors: Lucero, Héctor A., Ravid, Katya, Grimsby, Jessica L., Rich, Celeste B., DiCamillo, Sandra J., Mäki, Joni M., Myllyharju, Johanna, Kagan, Herbert M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Protein Synthesis, Post-Translational Modification, and Degradation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527118/
https://ncbi.nlm.nih.gov/pubmed/18586678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709897200
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