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Lysyl Oxidase Enhances Elastin Synthesis and Matrix Formation by Vascular Smooth Muscle Cells

Lysyl oxidase (LOX) is a copper-dependent enzyme which initiates covalent crosslinking of elastin precursors by oxidizing peptidyl lysine to aminoadipic semialdehydes. Previous studies have shown LOX deficiency to affect crosslinking of elastin and collagen in vivo, resulting in disorganized connect...

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Bibliografiske detaljer
Main Authors: Kothapalli, Chandrasekhar R., Ramamurthi, Anand
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828049/
https://ncbi.nlm.nih.gov/pubmed/19813219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/term.214
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