Induced Elastin Regeneration by Chronically-Activated Smooth Muscle Cells for Targeted Aneurysm Repair

Elastin breakdown in vascular aneurysms is mediated by cytokines such as tumor necrosis factor-α (TNF-α), which induces vascular smooth muscle cell (SMC) activation and regulates their deposition of matrix. We previously demonstrated exogenous supplement of TGF-β1 (1 ng/mL) and hyaluronan oligomers...

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Hlavní autoři: Kothapalli, Chandrasekhar R., Ramamurthi, Anand
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787710/
https://ncbi.nlm.nih.gov/pubmed/19505598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2009.06.006
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