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An Optimized Pentaplex PCR for Detecting DNA Mismatch Repair-Deficient Colorectal Cancers
PURPOSE: Microsatellite instability (MSI) is used to screen colorectal cancers (CRC) for Lynch Syndrome, and to predict outcome and response to treatment. The current technique for measuring MSI requires DNA from normal and neoplastic tissues, and fails to identify tumors with specific DNA mismatch...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2010
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2827558/ https://ncbi.nlm.nih.gov/pubmed/20195377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009393 |
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