Aberrant DNA Methylation in Hereditary Non-Polyposis Colorectal Cancer without Mismatch Repair Deficiency

BACKGROUND & AIMS: Approximately half of the families that fulfill Amsterdam criteria for Lynch syndrome or hereditary non-polyposis colorectal cancer (HNPCC) do not have evidence of the germline mismatch repair (MMR) gene mutations that define this syndrome and result in microsatellite instabil...

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Detalhes bibliográficos
Main Authors: Goel, Ajay, Xicola, Rosa M., Nguyen, Thuy-Phuong, Doyle, Brian J, Sohn, Vanessa R., Bandipalliam, Prathap, Reyes, Josep, Cordero, Carmen, Balaguer, Francesc, Castells, Antoni, Jover, Rodrigo, Andreu, Montserrat, Syngal, Sapna, Boland, C. Richard, Llor, Xavier
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859993/
https://ncbi.nlm.nih.gov/pubmed/20102720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.01.035
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