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Comprehensive molecular analysis of mismatch repair gene defects in suspected Lynch Syndrome (Hereditary Non-polyposis Colorectal Cancer) cases
An accurate algorithm is essential for effective molecular diagnosis of hereditary colorectal cancer. Here we have extended the analysis of 71 colorectal cancer cases suspected to be Lynch Syndrome cases for MSH2, MLH1, MSH6 and PMS2 gene defects. All cases were screened for mutations in MSH2, MLH1...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2761236/ https://ncbi.nlm.nih.gov/pubmed/19690142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-0358 |
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