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Sensitivity and specificity of clinical criteria for hereditary non-polyposis colorectal cancer associated mutations in MSH2 and MLH1

BACKGROUND AND AIMS—There are multiple criteria for the clinical diagnosis of hereditary non-polyposis colorectal cancer (HNPCC). The value of several of the newer proposed diagnostic criteria in identifying subjects with mutations in HNPCC associated mismatch repair genes has not been evaluated, an...

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Detaylı Bibliyografya
Asıl Yazarlar: Syngal, S., Fox, E., Eng, C., Kolodner, R., Garber, J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMJ Group 2000
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1734690/
https://ncbi.nlm.nih.gov/pubmed/10978352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.37.9.641
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