Mutation screening of MSH2 and MLH1 mRNA in hereditary non-polyposis colon cancer syndrome.

Germline mutations in four human mismatch repair genes (MSH2, MLH1, PMS1, and PMS2) have been reported to cause hereditary non-polyposis colon cancer syndrome (HNPCC). The identification of germline mutations in HNPCC kindreds allows precise diagnosis and accurate predictive testing. To investigate...

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Main Authors: Froggatt, N J, Brassett, C, Koch, D J, Evans, D G, Hodgson, S V, Ponder, B A, Maher, E R
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1996
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1050724/
https://ncbi.nlm.nih.gov/pubmed/8880570
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