Genetic linkage analysis in hereditary non-polyposis colon cancer syndrome.

Hereditary Non-polyposis Colon Cancer Syndrome (HNPCC) is the most common cause of familial colorectal cancer. Molecular genetic studies of HNPCC have shown evidence of locus heterogeneity, and mutations in four genes (hMSH2, hMLH1, hPMS1, and hPMS2) which encode components of the mismatch enzyme re...

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Autores principales: Froggatt, N J, Koch, J, Davies, R, Evans, D G, Clamp, A, Quarrell, O W, Weissenbach, J, Hodgson, S V, Ponder, B A, Barton, D E
Formato: Artigo
Lenguaje:Inglês
Publicado: 1995
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1050429/
https://ncbi.nlm.nih.gov/pubmed/7616541
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