Genetic linkage analysis in hereditary non-polyposis colon cancer syndrome.

Hereditary Non-polyposis Colon Cancer Syndrome (HNPCC) is the most common cause of familial colorectal cancer. Molecular genetic studies of HNPCC have shown evidence of locus heterogeneity, and mutations in four genes (hMSH2, hMLH1, hPMS1, and hPMS2) which encode components of the mismatch enzyme re...

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Detalhes bibliográficos
Main Authors: Froggatt, N J, Koch, J, Davies, R, Evans, D G, Clamp, A, Quarrell, O W, Weissenbach, J, Hodgson, S V, Ponder, B A, Barton, D E
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1050429/
https://ncbi.nlm.nih.gov/pubmed/7616541
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