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The Octarepeat Region of the Prion Protein Is Conformationally Altered in PrP(Sc)
BACKGROUND: Prion diseases are fatal neurodegenerative disorders characterized by misfolding and aggregation of the normal prion protein PrP(C). Little is known about the details of the structural rearrangement of physiological PrP(C) into a still-elusive disease-associated conformation termed PrP(S...
में बचाया:
| मुख्य लेखकों: | , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Public Library of Science
2010
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2827544/ https://ncbi.nlm.nih.gov/pubmed/20195363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009316 |
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