Mutations in Extensively Drug Resistant Mycobacterium tuberculosis that do not Code for Known Drug-Resistance Mechanisms

Highly-lethal outbreaks of multi drug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis are increasing. Whole-genome sequencing of KwaZulu-Natal MDR and XDR outbreak strains prevalent in HIV patients by the Broad Institute identified 22 novel mutations which were unique to the XDR ge...

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Detalhes bibliográficos
Main Authors: Motiwala, Alifiya S., Dai, Yang, Jones-López, Edward C., Hwang, Soo-Hee, Lee, Jong Seok, Cho, Sang Nae, Via, Laura E., Barry, Clifton E., Alland, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826498/
https://ncbi.nlm.nih.gov/pubmed/20136412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/650999
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