Evidence of Selective Sweeps in Genes Conferring Resistance to Chloroquine and Pyrimethamine in Plasmodium falciparum Isolates in India

Treatment of Plasmodium falciparum is complicated by the emergence and spread of parasite resistance to many of the first-line drugs used to treat malaria. Antimalarial drug resistance has been associated with specific point mutations in several genes, suggesting that these single nucleotide polymor...

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Autors principals: Mixson-Hayden, Tonya, Jain, Vidhan, McCollum, Andrea M., Poe, Amanda, Nagpal, Avinash C., Dash, Aditya P., Stiles, Jonathan K., Udhayakumar, Venkatachalam, Singh, Neeru
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
Matèries:
Mechanisms of Resistance
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826016/
https://ncbi.nlm.nih.gov/pubmed/20038626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00846-09
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