Evidence of Selective Sweeps in Genes Conferring Resistance to Chloroquine and Pyrimethamine in Plasmodium falciparum Isolates in India

Treatment of Plasmodium falciparum is complicated by the emergence and spread of parasite resistance to many of the first-line drugs used to treat malaria. Antimalarial drug resistance has been associated with specific point mutations in several genes, suggesting that these single nucleotide polymor...

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Bibliographische Detailangaben
Hauptverfasser: Mixson-Hayden, Tonya, Jain, Vidhan, McCollum, Andrea M., Poe, Amanda, Nagpal, Avinash C., Dash, Aditya P., Stiles, Jonathan K., Udhayakumar, Venkatachalam, Singh, Neeru
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Mechanisms of Resistance
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826016/
https://ncbi.nlm.nih.gov/pubmed/20038626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00846-09
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