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Evidence of Selective Sweeps in Genes Conferring Resistance to Chloroquine and Pyrimethamine in Plasmodium falciparum Isolates in India

Treatment of Plasmodium falciparum is complicated by the emergence and spread of parasite resistance to many of the first-line drugs used to treat malaria. Antimalarial drug resistance has been associated with specific point mutations in several genes, suggesting that these single nucleotide polymor...

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Autori principali: Mixson-Hayden, Tonya, Jain, Vidhan, McCollum, Andrea M., Poe, Amanda, Nagpal, Avinash C., Dash, Aditya P., Stiles, Jonathan K., Udhayakumar, Venkatachalam, Singh, Neeru
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826016/
https://ncbi.nlm.nih.gov/pubmed/20038626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00846-09
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