Evidence of Selective Sweeps in Genes Conferring Resistance to Chloroquine and Pyrimethamine in Plasmodium falciparum Isolates in India

Treatment of Plasmodium falciparum is complicated by the emergence and spread of parasite resistance to many of the first-line drugs used to treat malaria. Antimalarial drug resistance has been associated with specific point mutations in several genes, suggesting that these single nucleotide polymor...

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Detaylı Bibliyografya
Asıl Yazarlar: Mixson-Hayden, Tonya, Jain, Vidhan, McCollum, Andrea M., Poe, Amanda, Nagpal, Avinash C., Dash, Aditya P., Stiles, Jonathan K., Udhayakumar, Venkatachalam, Singh, Neeru
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2010
Konular:
Mechanisms of Resistance
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826016/
https://ncbi.nlm.nih.gov/pubmed/20038626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00846-09
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