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Intranasal Vaccinations with the trans-Sialidase Antigen plus CpG Adjuvant Induce Mucosal Immunity Protective against Conjunctival Trypanosoma cruzi Challenges

Trypanosoma cruzi is an intracellular protozoan parasite capable of infecting through mucosal surfaces. Our laboratory has previously elucidated the anatomical routes of infection after both conjunctival and gastric challenge in mice. We have shown that chronically infected mice develop strong immun...

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Detaylı Bibliyografya
Asıl Yazarlar: Giddings, O. K., Eickhoff, C. S., Sullivan, N. L., Hoft, D. F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825935/
https://ncbi.nlm.nih.gov/pubmed/20048046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00278-09
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