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Immune responses to gp82 provide protection against mucosal Trypanosoma cruzi infection

The potential use of the Trypanosoma cruzi metacyclic trypomastigote (MT) stage-specific molecule gp82 as a vaccine target has not been fully explored. We show that opsonization of T. cruzi MT with gp82-specific antibody prior to a relevant mucosal challenge significantly reduced parasite infectivit...

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Bibliographic Details
Main Authors: Eickhoff, Christopher S., Giddings, Olivia K., Yoshida, Nobuko, Hoft, Daniel F.
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150497/
https://ncbi.nlm.nih.gov/pubmed/20835618
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