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Type 1 Immunity Provides Optimal Protection against Both Mucosal and Systemic Trypanosoma cruzi Challenges

Chagas' disease results from infection with Trypanosoma cruzi, a protozoan parasite that establishes systemic intracellular infection after mucosal invasion. We hypothesized that ideal vaccines for mucosally invasive, intracellular pathogens like T. cruzi should induce mucosal type 2 immunity f...

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Detalhes bibliográficos
Main Authors: Hoft, D. F., Eickhoff, C. S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC132946/
https://ncbi.nlm.nih.gov/pubmed/12438346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.12.6715-6725.2002
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