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Pore Formation Triggered by Legionella spp. Is an Nlrc4 Inflammasome-Dependent Host Cell Response That Precedes Pyroptosis

Legionella pneumophila, the etiological agent of Legionnaires disease, is known to trigger pore formation in bone marrow-derived macrophages (BMMs) by mechanisms dependent on the type IVB secretion system known as Dot/Icm. Here, we used several mutants of L. pneumophila in combination with knockout...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Silveira, Tatiana N., Zamboni, Dario S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825914/
https://ncbi.nlm.nih.gov/pubmed/20048047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00905-09
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