Inflammasome activation triggers blood clotting and host death through pyroptosis

Inflammasome activation and subsequent pyroptosis are critical defense mechanisms against microbes. However, overactivation of inflammasome leads to death of the host. While recent studies have uncovered the mechanism of pyroptosis following inflammasome activation, how pyroptotic cell death drives...

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Publicado no:Immunity
Main Authors: Wu, Congqing, Lu, Wei, Zhang, Yan, Zhang, Guoying, Shi, Xuyan, Hisada, Yohei, Grover, Steven P., Zhang, Xinyi, Li, Lan, Xiang, Binggang, Shi, Jumei, Li, Xiang-An, Daugherty, Alan, Smyth, Susan S., Kirchhofer, Daniel, Shiroishi, Toshihiko, Shao, Feng, Mackman, Nigel, Wei, Yinan, Li, Zhenyu
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791531/
https://ncbi.nlm.nih.gov/pubmed/31076358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2019.04.003
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