Inflammasome activation triggers blood clotting and host death through pyroptosis

Inflammasome activation and subsequent pyroptosis are critical defense mechanisms against microbes. However, overactivation of inflammasome leads to death of the host. While recent studies have uncovered the mechanism of pyroptosis following inflammasome activation, how pyroptotic cell death drives...

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Bibliographic Details
Published in:Immunity
Main Authors: Wu, Congqing, Lu, Wei, Zhang, Yan, Zhang, Guoying, Shi, Xuyan, Hisada, Yohei, Grover, Steven P., Zhang, Xinyi, Li, Lan, Xiang, Binggang, Shi, Jumei, Li, Xiang-An, Daugherty, Alan, Smyth, Susan S., Kirchhofer, Daniel, Shiroishi, Toshihiko, Shao, Feng, Mackman, Nigel, Wei, Yinan, Li, Zhenyu
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791531/
https://ncbi.nlm.nih.gov/pubmed/31076358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2019.04.003
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