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Platelets protect from septic shock by inhibiting macrophage-dependent inflammation via the cyclooxygenase 1 signaling pathway

While it has been long known that patients with sepsis often have thrombocytopenia and that septic patients with severe thrombocytopenia have a poor prognosis and higher mortality, the role of platelets in the pathogenesis of sepsis is poorly understood. Here we report a protective role of platelets...

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Bibliografiska uppgifter
Huvudupphovsmän: Xiang, Binggang, Zhang, Guoying, Guo, Ling, Li, Xiang-An, Morris, Andrew J., Daugherty, Alan, Whiteheart, Sidney W., Smyth, Susan S., Li, Zhenyu
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217311/
https://ncbi.nlm.nih.gov/pubmed/24150174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3657
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