Regulation of Rap2A by the Ubiquitin Ligase Nedd4-1 Controls Neurite Development

Nedd4-1 is a ‘Neuronal Precursor Cell Expressed and Developmentally Downregulated Protein’ and among the most abundant E3 ubiquitin ligases in mammalian neurons. In analyses of conventional and conditional Nedd4-1 deficient mice, we found that Nedd4-1 plays a critical role in dendrite formation. Ned...

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Hauptverfasser: Kawabe, Hiroshi, Neeb, Antje, Dimova, Kalina, Young, Samuel M., Takeda, Michiko, Katsurabayashi, Shutaro, Mitkovski, Miso, Malakhova, Oxana A., Zhang, Dong-Er, Umikawa, Masato, Kariya, Ken-ichi, Goebbels, Sandra, Nave, Klaus-Armin, Rosenmund, Christian, Jahn, Olaf, Rhee, JeongSeop, Brose, Nils
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825371/
https://ncbi.nlm.nih.gov/pubmed/20159449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.01.007
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