Positron emission tomography imaging of tissue P-glycoprotein activity during pregnancy in the non-human primate

BACKGROUND AND PURPOSE: Changes in tissue P-glycoprotein (P-gp) activity during pregnancy could affect the pharmacokinetics and thus the efficacy and toxicity of many drugs. Therefore, using positron emission tomography (PET) imaging, we tested whether gestational age affects tissue P-gp activity in...

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Detalhes bibliográficos
Main Authors: Chung, FS, Eyal, S, Muzi, M, Link, JM, Mankoff, DA, Kaddoumi, A, O'Sullivan, F, Hsiao, P, Unadkat, JD
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825361/
https://ncbi.nlm.nih.gov/pubmed/20002098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00538.x
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